A wide range of markers, including regulation of CD3+, massive depletion of immature CD4+, CD8+ and mature CD4+, CD8-, and CD8- along with impaired regulation of immunoregulatory cytokines such as IFN-Υ, IL-10 and IL-2 for T-cell lymphoma, are listed in Table 3. This evidence concerns the gene CD8A and T-cell non-Hodgkin lymphoma.