According to KEGG pathway analysis, 259 DEGs primarily enriched in 13 pathways: staphylococcus aureus infection, cell cycle, vascular smooth muscle contraction, PPAR, proteoglycan in cancer, myocardial contraction, rheumatoid arthritis, arachidonic acid metabolism, hematopoietic cell lineage, cell adhesion molecules, drug metabolism - other enzymes, microRNAs in cancer, arginine and proline metabolism (Figure 2D). This evidence concerns the gene PPARA and rheumatoid arthritis.