Eleven tumor samples were tested for gene mutations by NSG, and only three of them carried mutated genes: one had a CYP2D6*10 homozygous mutation T/T and a UGT1A1*6 heterozygous mutation G/A, one had a PAK3 mutation, and one had a TP53 mutation (Supplementary Table 2). Here, CYP2D6 is linked to neoplasm.