Furthermore, immature oligodendrocyte markers, such as the chondroitin sulphate proteoglycan NG2 and platelet-derived growth factor receptor alpha (PDGFR-α), lack specificity (Popko et al., 2002) and have been unsuccessful in discerning between glioma types (Shoshan et al., 1999; Marie et al., 2001). Here, PDGFRA is linked to central nervous system cancer.