As shown in Table 3, DEGs in the CDs significantly affected biologically related functions and signaling pathways (Figures 6A–E) such as IL-4 Signaling Pathway (Figure 6B), RUNX3 Regulates Notch Signaling (Figure 6C), IL-1 and Megakaryocytes in Obesity Pathway (Figure 6D), and Overview of Leukocyteintrinsic Hippo Pathway (Figure 6E). The gene discussed is RUNX3; the disease is obesity due to melanocortin 4 receptor deficiency.