Models for ARS1-associated neuropathy have so far been generated for GARS1, YARS1, HARS1, and AARS1. There are currently no animal studies addressing dHMN9 caused by WARS1 mutations, CMT2U caused by MARS1 mutations, or for the form of CMT caused by SARS1 mutations. Here, MARS1 is linked to neuropathy.