GARS1 and Charcot-Marie-Tooth disease type 2D: Conditional expression of GlyRSG240R in the nervous system of Drosophila causes progressive motor deficits, and expression of GlyRSP234KY within the nervous system is lethal in the final stages of development, further demonstrating the neurotoxicity of CMT2D-associated GlyRS variants (Ermanoska et al., 2014).