LRRK2 and Parkinson disease: Mutations in LRRK2 are the most common genetic cause of both familial (41%) and sporadic (1–3%) PD (Jia et al., 2022; Oun et al., 2022) and among the function of LRRK2 that have been already clarified, it seems that its role in endomembrane trafficking may play a role in the pathogenesis of PD (Roosen and Cookson, 2016).