LRRK2 and Parkinson disease: Drosophila harbors a single LRRK2 orthologue gene (dLRKK) therefore it has been used to better understand the physiological functions of LRRK2 using loss of function models or overexpression of human LRRK2 variants responsible for PD (Hewitt and Whitworth, 2017; Seegobin et al., 2020).