Furthermore, Wei et al. (2022) found that transplantation of genetically corrected patient-specific iHeps by using CRISPR/Cas9 into immunodeficient Wilson’s disease (WD) mouse model can rescue the function of ATPase copper transporting beta (ATP7B) and disease phenotypes of WD characterized by improvement in liver function, reduced liver fibrosis and decreased hepatic copper accumulation due to copper-induced hepatotoxicity. The gene discussed is ATP7B; the disease is Wilson disease.