Ivanova et al. (2013) demonstrated promising results that liposomal prostaglandin E2 attenuated the extent of bleomycin-induced fibrosis in mice. Moreover, in clinical research, lipid metabolism-related products, such as amyloid A and adiponectin, are prognostic markers in clinical research (Vietri et al., 2019; d’Alessandro et al., 2020). Additionally, the activation of hypoxic response elements can modify glycolysis to promote the proliferation and differentiation of myofibroblasts during IPF progression (Dabral et al., 2019; Contreras-Lopez et al., 2020). The gene discussed is ADIPOQ; the disease is idiopathic pulmonary fibrosis.