SCN1A and encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy: Despite the modest number of mice used in this acute treatment pilot study, findings are consistent with those obtained by using CBD in a mouse model of Dravet syndrome (constitutive Scn1a deficient and knock-out or Scn1a+/−) wherein doses of 10 and 20 mg/kg CBD administered an hour before testing also enhanced social interaction in three chamber preference tests (28).