In 2020, Surmak et al. showed that a [11C]-PiB PET signal related to intracranial inflammation in MMA patients and a single relapsing-remitting multiple sclerosis (RRMS) patient may be corresponding to functional cerebral imaging of SULT1E1, suggesting that significant focal [11C]-PiB PET signals may be received from the inflamed living human brain (193). The gene discussed is SULT1E1; the disease is relapsing-remitting multiple sclerosis.