The synonymous variants found in the tumor in this study, such as MLH1 (rs769364808), FGFR3 (rs7688609), two variants in PDGFRA (rs1873778 and rs2228230), KIT (rs55986963), APC (rs41115), and RET (rs1800861) were reported previously in COSMIC, University of California Santa Cruz (UCSC), SNP, and ClinVar databases. This evidence concerns the gene APC and neoplasm.