SLC7A11 and colorectal carcinoma: The benzopyran derivative 2-imino-6-methoxy-2H-chromene-3-carbothioamide (IMCA), previously shown to inhibit CRC cell viability in vitro and tumor growth in vivo, was recently demonstrated to be a ferroptosis inducer in CRC cells [153, 154] through the down-regulation of SLC7A11 and decrease of cysteine and GSH levels.