RPS12 and Diamond-Blackfan anemia: One reason that genetic alterations in Rps12 have not yet been reported in DBA or other bone marrow failure disorders could be that Rps12 is not included in the most common targeted next-generation sequencing (NGS) panels used in the diagnosis of these disorders, some of which report molecular diagnostic rates of only 44–59% (Ghemlas et al., 2015; Muramatsu et al., 2017; Gálvez et al., 2021).