LH levels reached a maximum peak concentration at ∼4 h after triptorelin administration; peak LH stimulation was greatest in healthy women and lowest in women with FHA (mean LH change at 4 h 45.7 IU/L in healthy women, 31.3 IU/L in FHA, and 36.9 IU/L in PCOS), however the AUC of change in serum LH following triptorelin administration over 10 h did not differ between groups [70]. The gene discussed is PLOD1; the disease is polycystic ovary syndrome.