Previous studies have shown that GDF15 stimulates melanogenesis in melanocytes via β‐catenin signaling50 and that WNT‐β‐catenin‐T‐cell‐specific factor (TCF) signalling induces JAG1‐mediated induction of Notch signalling in gastric cancer.51 The gene discussed is HNF4A; the disease is gastric cancer.