IFN‐y is among the various cytokines produced en masse, with plasma levels of the cytokine increased in the blood of COVID‐19 patients who require intensive care (Huang et al, 2020), while B cells can recognize single‐stranded RNA viruses, including coronaviruses such as SARS‐CoV‐2, via TLR7 signaling (Lund et al, 2004; V'Kovski et al, 2021). Here, TLR7 is linked to COVID-19.