Protective integrins included ITGB7 in bladder urothelial cancer (BLCA), ITGA7 in liver hepatocellular carcinoma (LIHC), and ITGAD and ITGAE in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC). The gene discussed is ITGAE; the disease is bladder transitional cell carcinoma.