Elevated expression of ITGA7, ITGAD, ITGAE, ITGAL, ITGA4, and ITGB7 positively correlated with a higher degree of CD8+ T cell infiltration into tumor sites, whereas the expression of ITGB4, ITGA2, ITGA6, ITGA3, ITGB5, ITGB6, ITGB8, ITGA11, ITGA5, ITGAV, and ITGB1 were negatively correlated with CD8+ T cell infiltration in pancreatic cancer (Fig. 2D). Here, ITGB8 is linked to familial pancreatic carcinoma.