METTL3 and Infertility: From the analysis of the expression level of m6A regulators in dataset GSE120103, which includes fertile women with stage IV endometriosis and infertile women with stage IV endometriosis, we found that most m6A regulators, including METTL3, CBLL1, ALKBH5, FTO, YTHDC1, YTHDF2, IGF2BP2, HNRNPA2B1, HNRNPC, and LRPPRC, were significantly downregulated, while ZC3H13 and IGF2BP1 were significantly upregulated in infertile group versus fertile group (Fig. 1A, and Supplementary Fig. 1A).