PTH and anemia: Many factors have been incriminated in the pathogenesis including Th1/Th2 lymphocyte dysregulation, high levels of pro-inflammatory cytokines, increased mast cell activity, xerosis, neuropathy, dysregulation of the endogenous opioid system, anemia, uremic toxins, inadequate dialysis dose, imbalance of calcium, phosphate, and parathormone (PTH) [6–9].