IGHE and ascariasis: Trying to further explore this boosting effect in human ascariasis, we studied the evolution of the immune responses in children of the FRAAT birth cohort [16], finding that Ascaris-sensitized children had stronger IgE to B. tropicalis and those sensitized to the Ascaris allergen ABA-1 had increased IgE responses to Blo t 5 and Blo t 12, two species-specific allergens of B. tropicalis, ruling out the effect of cross-reactivity [17].