FGF2 and periodontitis: Kang et al. exploited the promotional effect of basic fibroblast growth factor (bFGF) on the proliferative capacity of PDLSCs and synergized its action with that of BMP-2 on PDLSCs to enhance the osteogenic and mineralizing capacity of PDLSCs while effectively compensating for the inhibitory effect on the osteogenesis of PDLSCs [24].Therefore, periodontal stem cells form the basis for slowing the resorption of periodontal bone tissue, promoting bone tissue repair and regeneration, and improving the prognosis of patients with periodontitis.