The −33 kb CRE, which to date is functionally uncharacterized, is only observed in 16HBE14o− cells and not in the CFTR‐expressing lung adenocarcinoma cell line Calu3 (Figure S2) or primary human bronchial epithelial cells (Kerschner et al., 2021; Suzuki et al., 2020). This evidence concerns the gene CFTR and lung adenocarcinoma.