TPT1/TCTP is the first target for inducing cancer reversion, which is currently in a clinical trial.[59] This gene forms a feedback loop with P53 which is known to mediate density‐dependent growth arrest.[60] In this case, we can presume that the density is an input node and the growth arrest is an output node of a subnetwork within the entire complex P53 network. Here, TP53 is linked to cancer.