TGFB1 and cancer: TGF‐b is well known to exert anti‐proliferative effects and regulate differentiation during normal development in various organs in vertebrates.[32] In contrast, growth inhibition via TGF‐b signaling is released and TGF‐b instead promotes invasion and metastasis in some cancers.[33] Likewise, KU‐1919 showed evading growth inhibition via TGF‐b signal in both our simulation of the Boolean network model and experimental validation (Figure 3A–G).