Gut microfloral metabolites, such as Lipopolysaccharide (LPS), Trimethylamine oxide (TMAO), and short-chain fatty acids (SCFA), affect CAD development through the immune response, inflammatory stimulation of nuclear factor kappa-B (NF-κB), lipid metabolism, and bile acid metabolism [11–13]. This evidence concerns the gene NFKB1 and coronary artery disorder.