ESR1 and neoplasm: We further examined the relationship between HSPB1 expression and clinical characteristics, including the patient status (tumor or normal) (Fig. 2A), age (≤ 60 and > 60) (Fig. 2B), T stage (T1, T2, T3, or T4) (Fig. 2C), N stage (N0, N1, N2, or N3) (Fig. 2 D), M stage (M0 or M1) (Fig. 2E), pathologic stage (stage I, stage II, or stage III) (Fig. 2F), ER (negative or positive) (Fig. 2G), PR (negative or positive) (Fig. 2H).