HBP1 and neoplasm: Blv-miR-B4-3p shares seed sequence similarities with the host miRNA miR-29a, which is known to downregulate the expression of two tumor suppressor genes, the genes coding for the HMG-box transcription factor 1 (HBP1) [129] and for the peroxidasin homolog (PXDN) [130], in B-cell tumors.