The results from the TCGA database were used to explore the correlation between CLSPN expression and clinicopathological stages in various cancers, which revealed the stage-specific expressional changes of CLSPN in some tumor types, such as BRCA, KICH (Kidney Chromophobe), KIRC, LIHC, LUAD, et al. (Supplementary Figure S2A-T). This evidence concerns the gene CLSPN and chromophobe renal cell carcinoma.