LBH and cancer: Notably, DNA methylation levels at the LBH gene locus were significantly lower in cancers with LBH overexpression: i.e., colon-rectal (COAD, READ; p < 0.01), pancreatic (PAAD; p < 0.0001), esophageal (ESCA; p < 0.01), liver (LIHC; p < 0.0001), kidney (KIRC, p < 0.0001; KIRP, p < 0.001), bladder (BLCA; p < 0.05), head and neck (HNSC; p < 0.0001) (Fig. 4A; top row).