TMPRSS2 and Hepatic steatosis: It has been hypothesized that this link between MAFLD and severity of respiratory manifestations could be explained by the fact that the angiotensin-converting enzyme 2 receptors and the cellular serine protease TMPRSS2 (ACE2/TMPRSS2), used by SARS-CoV-2 [10–12], are more expressed in patients with metabolic-associated hepatic steatosis or steatohepatitis, with a possible facilitation to the entrance of the virus in the cells [13–15], while taking into account that the study by Meijnikman et al. is based on RNA transcriptomic, and not directly on protein levels or ACE2 activity [14].