USP5 and cancer: Meanwhile, for immune subtypes (C1: wound healing, C2: IFN-gamma dominant, C3: inflammatory, C4: lymphocyte depleted, C5: immunologically quiet, C6: TGF-b dominant), we found that USP5 expression was significantly different in 14 of 30 cancers, including BLCA, BRCA, HNSC, KICH, KIRC, KIRP, LIHC, LUAD, LUSC, MESO, OV, PCPG, SKCM and STAD (Fig. 5A–N).