In the serum, the concentrations of four cytokines, IL-2Rα, IP-10, MIP-1α and SCGF-BB, were elevated in bvFTD compared to controls, while GRO-α, IFN-α2, IL-18, MCP-1, MIP-1β and PDGF-BB have shown time-dependent increase in serum concentration with disease progression. This evidence concerns the gene IL18 and behavioral variant of frontotemporal dementia.