The geometric mean concentration (GMC) levels of IgA was less than 2 U/mL in both Rotavirus-positive and Rotavirus-negative cases at the acute phase which is lower than the seroconversion rate (20 U/mL) suggesting that these were vaccine failures as they were all vaccinated with Rotarix rotavirus vaccine prior to presenting with diarrhoea. The gene discussed is CD79A; the disease is Diarrhea.