CD79A and Proteinuria: Nephrotic proteinuria is uncommon and, if present, is usually associated with severe histological features including endocapillary proliferation, segmental sclerosis, and crescent formation linked to subendothelial IgA deposits.[14] One subset of patients with IgAN who present with nephrotic proteinuria show only mild mesangial proliferative IgAN on histological examination.