MCM3AP and cancer: It has been reported that miR-448 could target myocyte enhancer factor 2 (MEF2) to promote the proliferation of VSMC.[12] Our bioinformatic analysis revealed that miR-448 was predicted to interact with MCM3AP-AS1, an oncogenic lncRNA that has been implicated in several types of cancer.[13–16] We hypothesized that MCM3AP-AS1 may interact with miR-448, thereby indirectly regulating the expression of MEF2.