Moreover, we further investigated the association between FGF19 and other scales, such as SAS, HAMD, and HAMA, and came to the similar conclusion that the plasma FGF19 levels were also positively correlated with other scales’ scores, which provide evidence of the role of FGF19 in mood regulation including both depressive and anxiety behaviors in patients with depression. The gene discussed is FGF19; the disease is depressive disorder.