We discovered the renal fibrosis group had higher levels of mast cells activated, neutrophils, T cells CD8, T cells CD4 memory cells activated, T cells follicular helper, and T cells gamma delta, while macrophages M2, mast cells resting, NK cells activated, and CD4 memory resting content were lower than control group (Figure 6A). The gene discussed is CD4; the disease is renal fibrosis.