RNASE3 and asthma: Although it seems to be unspecific for the diagnosis of eosinophil-associated respiratory diseases such as asthma, ECP is considered as a useful biomarker of airway inflammation and its abundance in peripheral blood has been associated to the control of asthma, and considered as a good biomarker to monitor the efficacy of classical and new biological therapies used in the treatment of this disease (44–47).