The hippocampal dentate gyrus slices of rats with 5-Bromo-2′-deoxyuridine single labeling (BrdU+) and BrdU/neuron nuclear antibody double labeling (BrdU+/NeuN+) showed that the number of BrdU+ cells in anxiety model rats increased, while the JWXYS treated rat showed a significant increase in the number of BrdU+ and BrdU+/NeuN+ cells. Here, RBFOX3 is linked to Anxiety.