The authors additionally observe differential expression of the ADAM (A Disintegrin And Metalloproteinase) and ADAMTS (A Disintegrin And Metalloproteinase with Thrombospondin Motifs) families of ECM remodeling enzymes (Roy et al., 2004; Keating et al., 2006; Janssen et al., 2016), with ADAM33 and ADAMTSL4 repressed relative to mock-infected cells at 1 hour post-infection and ADAM12, ADAM19, ADAMTS3, and ADAMTS6 induced at both 1 and 24 hours post-infection. This evidence concerns the gene ADAM12 and infection.