TGFB1 and infection: Pharmacological inhibition of either the TGF-β or EGF receptors (using SB-431542 or Gefitinib/ZD-1839, respectively) significantly attenuated infection-dependent repression of E-cadherin, suggesting that Chlamydia-induced TGF-β may act in an autocrine fashion on infected cells to promote EMT (Igietseme et al., 2020).