In particular, we demonstrated relative sparing of the rectus femoris, comparative lesser involvement of the adductor longus compared to the adductor magnus, involvement of the sartorius, comparative sparing of the gracilis and notable involvement of the soleus in the lower leg; findings that are similar to those observed in RYR1 congenital myopathy (Fig. 3).10, 47. This evidence concerns the gene RYR1 and congenital myopathy with cores.