POU3F2 and small cell lung carcinoma: However, several genes are found within the confidence interval, including Pou3f2 and Mms22l. POU family transcription factors were previously shown to be highly expressed in small-cell lung carcinoma (SCLC) cell lines and to contribute to neuroendorcrine differentiation in non-small cell lung carcinoma (NSCLC) cell lines[63].