TG and obesity due to melanocortin 4 receptor deficiency: To date, thyroid hormone sensitivity indices have been revealed to be associated with obesity [13, 17, 27], prediabetes [28], diabetes [13, 14], gestational diabetes [29], hypertension [14], metabolic syndrome [13], non-alcoholic fatty liver disease [30], renal function [15, 31], homocysteine levels [32], hyperuricemia [17], cardiovascular disease [17], diabetes-related mortality [13], and all-cause mortality [16].