The magnitude of association for genetically adjusted baseline PSAG with prostate cancer (OR per unit increase in log(PSA ng ml−1) = 1.90, 95% CI: 1.56–2.31) was slightly larger than for PSA (OR = 1.88, 95% CI: 1.55–2.29) in the European ancestry group (Supplementary Table 17). The gene discussed is KLK3; the disease is prostate cancer.