LINC00881 and type 2 diabetes mellitus: Since LIPTER expression is enriched in human CMs and downregulated in T2DM hearts (Figs. 1, b,c and 4a) and extensive LDs were observed in both LIPTERKO and T2DM human CMs (Figs. 2, b,c and 4b,c), we posited that LIPTER transcription was under the control of a CM-specific regulatory mechanism that could respond to hyperglycaemia.