We identified the top four CM-enriched lncRNAs, LINC00881, TTN-AS1, SLC8A1-AS1 and NAV2-AS2, which were downregulated in T2DM hearts compared with non-T2DM hearts (Fig. 1a,b and Extended Data Fig. 1a). This evidence concerns the gene SLC8A1 and type 2 diabetes mellitus.