Finally, LIPTER overexpression was found to repress NKX2.5KD-induced LD accumulation and apoptosis (Extended Data Fig. 5b–e, shNKX2.5 versus shControl in LIPTERKO/OE CMs), suggesting a therapeutic potential of LIPTER for treating diabetes-associated dilated cardiomyopathy (DCM)34. The gene discussed is LINC00881; the disease is familial dilated cardiomyopathy.