In summary, high LKB1 expression is associated with tumor size (P < 0.01), degree of differentiation (P < 0.001), depth of invasion (P < 0.001), lymph node metastasis (P = 0.01), and TNM stage (P < 0.01) of GC which reflected the ability of proliferation and metastasis of GC. Here, STK11 is linked to neoplasm.