STK11 and neoplasm: Therefore, we performed the meta-analysis to investigate the relationship between LKB1 expression and the clinicopathological parameters and prognostic value of GC patients and found: (1) LKB1 expression is not associated with gender or age; (2) LKB1 expression is significantly correlated with tumor size, degree of differentiation, depth of invasion, lymph node metastasis, and TNM stage; (3) LKB1 expression is significantly correlated with OS; and LKB1 low expression is a risk factor for poor prognosis.