CEACAM5 and lung cancer: Compared with the PLCOm2012 model9, a well-performing prediction model for smoking-related lung cancer which uses questionnaire information, the individual proteins improved discrimination between future lung cancer cases and controls by between 0.005 (OSM) and 0.082 (CEACAM5) units in the area under the receiver operating curve (AUC) (Supplementary Data 4).