- CCDC3 suppresses BrC growth (Li et al., 2023a)- CCDC3 prevents MDM2-mediated recruitment of p53 to the 19S proteasome (Li et al., 2023a)- CCDC3 is upregulated by p53 (Li et al., 2023a)- CCDC3 can inhibit migration and invasion of PC-3 and DU145 prostate cancer cells (Ke et al., 2022)- CCDC3 knockdown leads to the inhibition of migration, proliferation, invasion, and EMT in C33 and HeLa cervical cancer cells (Zhang et al., 2019). The gene discussed is MDM2; the disease is Familial prostate cancer.