TNF and cancer: Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis analyzed differentially expressed genes (DEGs) between TB‐5 and Library treatment separately, revealing that the genes regulated by TB‐5 were significantly enriched in pathways including transcriptional misregulation in cancer, tumor necrosis factor‐alpha (TNF) signaling, Notch signaling, NF‐kappa B signaling and transforming growth factor‐beta (TGF‐beta) signaling (Figure 8J).