We recently reported again on Mtb-infected Nod2-KO mice (C57BL/6) while investigating dual (NOD2 and Mincle) PRR knockout: After aerosol infection with 15 CFU H37Rv, there was no significant effect on bacterial burden and pulmonary leukocyte infiltration by 6 weeks postinfection [73]. The gene discussed is NOD2; the disease is infection.